Natural killer cell activity in untreated systemic lupus erythematosus.
نویسندگان
چکیده
With strictly selected controls natural killer cell activity was evaluated in 10 untreated patients with systemic lupus erythematosus. Natural killer levels of the patients were significantly lower than those of the age- and sex-matched normal controls. Natural killer levels, however, did not correlate with disease activity.
منابع مشابه
Recent findings on the role of natural killer cells in the pathogenesis of systemic lupus erythematosus.
Systemic lupus erythematosus is a chronic, multifactorial autoimmune disease of complex etiology, characterized by loss of tolerance to nuclear autoantigens, expansion of autoreactive T and B cell clones, polyclonal B cell activation that gives rise to hypergammaglobulinemia, and increased autoantibody production, as well as immune complex deposition and multiorgan tissue inflammation. As disea...
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ورودعنوان ژورنال:
- Annals of the rheumatic diseases
دوره 41 4 شماره
صفحات -
تاریخ انتشار 1982